{"id":263,"date":"2023-02-24T09:43:28","date_gmt":"2023-02-24T09:43:28","guid":{"rendered":"http:\/\/192.168.10.30\/?page_id=263"},"modified":"2023-03-06T12:06:25","modified_gmt":"2023-03-06T12:06:25","slug":"approach","status":"publish","type":"page","link":"https:\/\/rttrialsqa.org.uk\/?page_id=263","title":{"rendered":"Approach"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

Analysis of Proton vs. Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health<\/p>\n\n\n\n

Trial summary: <\/strong>APPROACH is phase III, multi-centre, randomised trial which aims to compare proton beam therapy (PBT) with photon radiotherapy \u00a0to assess whether there are early (2 years post RT) and long-term (5 years post-RT) signals of neurocognitive benefit with PBT compared to photon RT \u00a0in adult patients with oligodendroglioma. 246 patients will be recruited from UK sites.<\/p>\n\n\n\n

RT QA summary:<\/h2>\n\n\n\n

All QA activity will be streamlined with previous trial QA, where applicable. Please contact the RTTQA Group directly using the contact details below to discuss.<\/em><\/p>\n\n\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
QA Process<\/th>QA Activity<\/th>Required for Trial<\/th>Additional Details<\/th>\n<\/tr>\n<\/thead>\n
Pre-Accrual<\/td>Facility Questionnaire<\/td>\"\"<\/td><\/td>\n<\/tr>\n
Outlining Benchmark Case<\/td>\"\"<\/td>1 case<\/td>\n<\/tr>\n
Planning Benchmark Case<\/td>\"\"<\/td>1 case<\/td>\n<\/tr>\n
Dummy Run<\/td><\/td><\/td>\n<\/tr>\n
During Accrual<\/td>Individual Case Review<\/td>\"\"<\/td>Retrospective: all patients<\/td>\n<\/tr>\n
Data collection<\/td>\"\"<\/td>All patients<\/td>\n<\/tr>\n
Dosimetry <\/td><\/td>\"\"<\/td><\/td>\n<\/tr>\n
QA Streamlining<\/td><\/td>\"\"<\/td>PARADIGM, PARADIGM2, ROAM, HIPPO, BRIOChe
\n
\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n

RTTQA contact:<\/strong> ccf-tr.approachqa@nhs.net<\/a> <\/p>\n\n\n\n

Chief investigator: <\/strong> Dr Louise Murray , <\/strong>Yorkshire Cancer Research Associate Professor and Honorary Consultant Clinical Oncologist<\/p>\n\n\n\n

Sponsor: <\/strong>University of Leeds  approach@leeds.ac.uk<\/a><\/p>\n\n\n\n

Funder: <\/strong> National Institute for Health and Care Research (NIHR) Efficacy and Mechanism Evaluation (EME) Programme (Ref: NIHR131082)<\/p>\n","protected":false},"excerpt":{"rendered":"

Analysis of Proton vs. Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health Trial summary: APPROACH is phase III, multi-centre, randomised trial […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-263","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=\/wp\/v2\/pages\/263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=263"}],"version-history":[{"count":3,"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=\/wp\/v2\/pages\/263\/revisions"}],"predecessor-version":[{"id":304,"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=\/wp\/v2\/pages\/263\/revisions\/304"}],"wp:attachment":[{"href":"https:\/\/rttrialsqa.org.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}